MAK JOON WAH

Title : Professor, Pro Vice-Chancellor (Research) and Director, IRDI
Department : School of Postgraduate Studies & Research

Contact Information :
Institute for Research, Development and Innovation (IRDI), International Medical University

Tel : 03-27317298; Fax : 03-86567299
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it

 

Education and Training

MRC Path / FRC Path
UK
1983/1995
MD University of Singapore, 1980
MPH University of Malaya,
1976
DAP&E SEAMEO-TROPMED-Malaysia,
1972
MBBS University of Singapore,
1967

 

Research interests:

  • Tropical Medicine
  • Parasitology
  • Molecular Biology



Research projects/grants:

International (as Principal Investigator)

  • WHO/TDR Grant for 'In vitro cultivation of Brugia malayi and Brugia pahangi' (ID 790015), US$5,000 (1981).
  • WHO/TDR Grant for 'Screening potential filaricides against Brugia malayi in non-human primates, Presbytis spp.' - US$121,820 (1982- 1985).
  • WHO/VBC Grant for 'Provision of blood meal identi¬fication of vectors' - US$5,000 (1987).
  • WHO/TDR Grant for 'Screening of potential filari¬cides against Brugia malayi in Presbytis cristata spp.' -, I.D. 860304; US$186,080 (1986-1990).
  • WHO/TDR Grant for 'Testing filaricides against Brugia malayi in leaf-monkeys' - I.D. 87013, US$49,700 (1987-1989)
  • WHO/TDR Grant for 'Ivermectin trials against sub-periodic Brugia malayi infection in Malaysia' - I.D. 890099, US$47,700 (1989-91).
  • WHO/TDR Grant for 'Antifilarial drug testing in vitro and in vivo - I.D.910334, US$20,000 (1992/93).
  • WHO/WPRO Grant on ‘Regional collaboration for rapid malaria diagnosis in Southeast Asia and China’ - US$20,000 (1995/96)


National Research & Development Grants:

  • MPKSN Grant for 'Production and use of monoclonals against Brugia malayi and Brugia pahangi - $19,000 (1984).
  • 'Development of immunodiagnostic tests for toxoplasmosis and toxocariasis'- $160,000 (1988-90).
  • 'Production and use of DNA probes for malaria and other parasitic diseases'- $240,000.
  • 'Epidemiology of malaria among Orang Asli and rural communities' - $37,721 (1988-90).
  • 'Immunodiagnosis of malaria for clinical diagno¬sis and epidemiological studies' - $35,000.
  • 'Characterization of sera of Brugia malayi infected Presbytis spp. by immunotransfer blot technique'- $11,944 (1988-89).
  • 'Studies on the immune response of Presbytis cristata infected with Brugia malayi before and after treatment with DEC, Ivermectin and CGP20376'- $21,400 (1988).
  • 'Studies on the biology and immunology of Toxo¬plasma gondii' - $3,500 (1988).
  • ‘Development and use of immunodiagnostic tests for parasitic diseases' - $20,500 (1988).
  • 'Pathoimmunology of visceral larval migrans due to Toxocara infection' - $46,428 (1989-90).
  • 'Development and use of monoclonal antibodies for immunological studies and diagnosis of toxoplasmosis (R&D IMR 91-22)' - RM55,500 (1991); RM21,500 (1992); RM21,500 (1993).
  • 'Production, characterization and use of Toxoca¬ra monoclonal antibodies (R&D IMR 91-23)' - RM 20,500 (1991); RM21,500 (1992); RM21,500 (1993).
  • 'Studies on the cell-mediated immune responses and pathology in Brugia malayi infection (R&D IMR 91-24)' - RM57,000 (1991); RM19,500 (1992).
  • 'The role of cell-mediated immunity in toxoplas¬mosis (R&D IMR 91-25) - RM26,000 (1991); RM24,500 (1992).
  • 'Seroepidemiology and drug sensitivity studies in malaria (R&D IMR 91-26)' - RM20,000 (1991); RM20,00 (1992).
  • 'Production of fusion proteins of Toxocara canis infective larvae and adult worm, primarily as antigen source in the immunodiagnosis of toxo¬cariasis (R&D IMR 91-27) - RM37,150 (1991); RM13,500 (1992).
  • 'Toxicity of aflatoxin in Macaca fascicularis (NIMR 49-2) - RM17,000 (1991).
  • 'Development and use of monoclonal antibodies for parasitic diseases with special emphasis on malaria, filariasis, toxocariasis and toxoplas¬mosis (National Biotechnology Programme - Sub-programme Medical Biotechnology, B.U.2) - RM58,000 (1991); RM34,568 (1992); RM40,000 (1993); RM60,000 (1994).
  • WHO/TDR Grant for 'Screening potential filaricides against B. malayi infection in Presbytis spp.' (ID 910334) - US$ 47,540 (1 December 1991-30 November 1992).
  • 'Molecular biology of pathogenic and non-pathogenic strains of Entamoeba histolytica (R&D IMR 94-42) - RM134,200 (1994).
  • ‘Molecular approaches to determination of biomarkers for diseases and disease susceptibility, and development of appropriate techniques for diagnosis - parasitic and neoplastic diseases’ -RM 161,000 (1996/97).
  • “Production of monoclonal antibody against Candida albicans – IMU 026-2002 – RM 8000 (2002/2003).
  • “A study on the changes in blood glucose levels and othe biochemical parameters induced in normal mice by TCM Complex for diabetes (TCM-D)” – IMU R10-2002 – RM 9600 (REM Corporation) (2002-2004).
  • “A study on the blood glucose levels in diabetic mice treated with TCM complex for diabetes (TCM-D)” – IMU R11-2002 – RM 19200 (REM Corporation) (2002-2004).
  • “Molecular studies on disease biomarkers and pathogenesis of cancer: colorectal carcinoma as a model” – IRPA National Biotechnology 06-05-01-003 BTK/ER 018, RM 146,358 (2002-2004).
  • “Development of immunoassays for the detection of Candida antigens in systemic candidiasis” – IRPA National Biotechnology 06-02-04-005 BTK/023, RM 345316 (2003-2005).
  • “Molecular and immunological characterisation of pathogenic and non-pathogenic Acanthamoeba species in Malaysia” – IMU 086-05; RM 39,000 (2005-2007).
  • “The prevalence of Acanthamoeba in ventilation system and its Association with Other Environmental Microorganisms as an Indicator for Indoor Air Quality” – IMU RM 50,000 (2008-2010).
  • Functional roles of DNA-methyltransferase and histone-deacetylases on the regulation of genes encoding virulence-associated proteins in Acanthamoeba species. FRGS/1/2014/SKK05/IMU/03/1; Chan Li Li et al.; RM 114,920.00 (2014-2016).
  • Biomarkers of polar and lower latitude microbes in relation to heavy metal stress. National Antartic Research Centre/IMU R148/2014/CWL et al.; RM 819,902 (2014-2016)
  • The influence of Wolbachia on susceptibility to insecticide in Aedes mosquitoes and its underlying mechanism of action. FRGS/1/2016/SKK11/IMU/02/1; Wong SF et al. RM 113,000, 2016-2018.

 

Supervision of Postgraduates (MSc/PhD)
(Last 5 years – 2010-2014)

  • Production of polyclonal and monoclonal antibodies against the Brugia malayi BmR recombinant protein for use in the development of a filarial antigen detection assay – Cheong Poi Yee, MSc Project, 2007-2011.
  • Production of recombinant allergen and monoclonal antibody for diagnosis of house dust mite allergy in Malaysia – Wong Siew Tung, PhD Candidate, 2007 onwards.
  • The prevalence of Acanthamoeba in ventilation system and its association with other environmental organisms as an indicator for indoor air quality – Ooi Soo Shen, PhD Candidate, 2008-2014.
  • Vasala Ramachandran (PhD candidate). Project Title: Anticoagulant action of Morinda citrifolia fruit extract: mechanism of action and chemical characterization. Researchers: Yeoh PN, Mak JW, Mallikarjuna P Rao. 2010-2012.
  • Mehru Nisha Muhamad Haneef (PhD candidate). Project Title: Determining the pattern and behavioural predictors of gastrointestinal parasitic infections in the Orang Asli using molecular techniques and classical methods of identification of gastrointestinal parasite. Researchers: Verasingam Kumarasamy, Stephen Ambu, Mak JW. 2011-2013.
  • Justin Chellian (PhD student). Project Title: Exploring the potential for quercetin potentiation of the cardiovascular effects of a thiazolidinedione and a biguanide anti-diabetic drug. Reseachers: Framcis Archike, Mak JW, Mohd Rais Mustafa, Mallikarjuna Rao, Yiap Beow Chin. Start: 2011-to date.
  • Voon Yit Nee (MSc Candidate): Expression and roles of Interferon Regulatory Factor-5 (IRF5) in asthmatic and non-asthmatic patients. 2014-2016.


 

Professional affiliations:

  • Medical Association of Malaysia
  • Malaysian Society of Parasitology and Tropical Medicine
  • College of Pathology Malaysia
  • Fellow of Academy of Medicine Malaysia
  • Foundation Fellow of the Academy of Sciences Malaysia

 

Academic Awards:

  • Malaysian Society of Parasitology and Tropical Medicine Medal, 1981
  • National Science Award, Malaysia, 1985
  • Sandosham Gold Medal, MSPTM, 1986
  • Merdeka Award for Outstanding Scholastic Achievement, 2011
  • Doctor of Science (Hon Causa), IMU, 2015

 

Recent publications
(last 5 years – 2010 - 2014)

2010

 

  • Cho Naing, Kyan Aung, Daw-Khin Win, Mak JW. Efficacy and safety of chloroquine for treatment in patients with uncomplicated Plasmodium vivax infections in endemic countries. Trans Roy Soc Trop Med Hyg, 2010; doi:10.1016/j.trstmh.2010.08.009 [IF: 2.553]
  • Choo ZW, Chakravarthi S, Wong SF, Nagarajah HS, Thanikachalam PM, Mak JW, Radhakrishnan A, Tay A. Comparative histological study of systemic candidiasis in association with experimentally induced breast cancer. Oncology Letters 2010; 1: 215-222.
  • Pan Y, Abd-Rashid BA, Ismail Z, Ismail R, Mak JW, Pook PC, Er HM, Ong CE. In vitro modulatory effects on three major human cytochrome P450 enzymes by multiple active constituents and extracts of Centella asiatica. J Ethnopharmacol, 2010; 130: 275-283. [IF: 2.322]
  • Srikumar Chakravarthi, Choo Zhen Wei, Nagaraja HS, Wong Shew Fung,  Mak Joon Wah,  Thani PM,  Radhakrishnan A, Tay A. Immunosuppressive effect of disseminated breast carcinoma on severity of hepatic candidiasis. Res J Immunol, 2010; 3 (1): 1-11. (ISSN: 1994-7909). [IF: NA]
  • Srikumar Chakravarthi, Choo Zhen Wei, Nagaraja HS, Wong Shew Fung, Mak Joon Wah, Shalini Sree Kumar. A histopathological study of severity of cerebral candidiasis as a result of immunosuppression caused by breast carcinoma. Internat J Mol Med Adv Sci, 2010, 6 (1):1-7; (ISSN: 1994-4624). [IF: NA]
  • Wong Shew Fung, Mak JW. Candida parapsilosis-specific monoclonal antibodies and their use for detection of Candida antigens in experimental systemic candidiasis. Hybridoma 2010; 29: Doi: 10.1089/hyb.2010.0049 [IF: 2.35]

 

2011

 

  • Chan Li-Li, Mak Joon-Wah, Low Yoon-Tong, Koh Thuan-Tzen, Shar Mariam Mohamed. Isolation and characterization of Acanthamoeba spp. from air-conditioners in Kuala Lumpur, Malaysia. Acta Tropica 2011; 117: 23-30 [IF: 2.373]
  • Init Ithoi, Arine-Fadzlun Ahmad, Mak JW, Veeranoot Nissapatorn, Yee Ling Lau, Rohela Mahmud. Morphological characteristics of developmental stages of Acanthamoeba and Naegleria species before and after staining by various techniques. Southeast Asian J Trop Med Pub Hlth (Thailand) 2011; 44(6): 1-12. [IF: 2.55]
  • Init Ithoi, Arine Fadzlun Ahmad, Veeranoot Nissapatorn, Yee Ling Lau, Rohela Mahmud, Joon Wah Mak. Detection of Naegleria species in environmental samples from Peninsular Malaysia. PLoS ONE (US) 2011; 6(9): e24327. Doi10.1371/journal.pone.0024327. [IF: 4.441]
  • Init Ithoi, Azman Jali, Mak JW. Wan Yusoff Wan Sulaiman, Rohela Mahmud. Occurrence of Blastocystis in water of two rivers from recreational areas in Malaysia. J Parasitol Res 2011; doi: 10.1155/2011/123916. [IF: NA].
  • Kok YY, Chu WL, Phang SM, Shar Mariam Mohamed, Rakesh Naidu, Lai PJ, Ling SN, Mak JW, Lim KC, Balraj P, Khoo ASB. Inhibitory activities of microalgal extracts against Epstein-Barr virus DNA release from lymphoblastoid cells. J Zheijiang Univ-Sci B (Biomed&Biotechnol) 2011; 12(5): 335-345 [IF: 1.679]
  • Pan Yan, Badrul Amini Abd-Rashid, Zakiah Ismail, Rusli Ismail, Mak JW, Pook PCK, Er Hui Meng, Ong CE. In vitro effects of active constituents and extracts of Orthosiphon stamineus on the activities of three major human cDNA-expressed cytochrome P450 enzymes. Chemico-Biological Interactions 2011; 190 (1): 1-8. Doi: 10.1016/j.cbi.2011.01.022. [IF: 2.832]
  • Pan Yan, Abd-Rashid BA, Ismail Z, Ismail R, Mak JW, Pook PC, Er HM, Ong CE. In vitro modulating effects of Adrographis paniculata, Centella asiatica and Orthosiphon stamineus on cytochrome P450 2C19 (CYP2C19). J Ethnopharmacol 2011; 133(2): 881-887. [IF: 2.322]
  • Pan Yan, Badrul Amin AR, Zakiah I, Rusli Ismail Mak JW, Ong CE. Heterologous expression of human cytochromes P450 2D6 and CYP3A4 in Escherichia coli and their functional characterisation. Protein J 2011; 30: 581-591; doi: 10.1007/s10930-011-9365-6. [IF: NA]
  • Quah JX, Ambu S, Lim YAL, Mahdy MAK, Mak JW. Molecular identification of Cryptosporidium parvum from avian hosts. Parasitol 2011; 138: 573-577 [2.522]
  • Srikumar Chakravathi, Nagarajah HS, Choo Zhen Wei, Wong SF, Mak JW, Radhakrishnan A. The Cardiology 2011; 6(1): 1-7.
  • Tang JC, Wong SF, Mak JW, Ho TM. Antigenic profile of Blomia tropicalis, Aleuroglyphus ovatus and Glycycometus malaysiensis. Tropical Biomedicine 2011; 28(2): 223-236. [IF: 0.5]
  • Wong SF, Chong Ai Ling, Mak JW, Tan Jessie, Ling Suk Jiun, Ho Tze Ming. Molecular identification of house dust mites and storage mites. Experimental and Applied Acarology 2011; DOI 10.1007/s10493-011-9460-6. [IF: 1.391]

 

2012

 

  • Abdulsalam AM, Ithoi I, Al-Mekhalafi HM, Ahmed A, Surin J, Mak JW. Drinking water is a significant predictor of Blastocystis infection among rural Malaysian primary schoolchildren. Parasitology 2012; 139(8): 1014-1020. (SCI IF: 2.961; HI: 70; Tier: Q1); (ISI IF: 2.961).
  • Cho Naing, Aung K, Ahmed SI, Mak JW. Signal detection to identify serious adverse events (neuropsychiatric events) in travelers taking mefloquine for chemprophylaxis of malaria. Drug, Healthcare and Patient Safety 2012; 4(1): 87-92. (SCI IF: 0.515; HI: 3; Tier: Q3).
  • Cho Naing, Kyan Aung, Mak JW. Reporting ‘number needed to treat’ in meta-analyses: A cross-sectional study. Journal of Evidence-based Medicine 2012; 5: 232-237; doi: 10.1111/jebm.12002. (SCI IF: 1.245; HI: 6; Tier: Q2)
  • Cho Naing, Mak JW, Nyunt Wai, Mala Maung. Diabetes and infectious hepatitis C (Is there type 2 diabetes excess in hepatitis C-infection?). Current Diabetes Reports (in press). (ISI IF: 2.496; IF: 2.974; HI: 35; Tier: Q1).
  • Cho Naing, Mak JW, Syed Imran Ahmed, Mala Maung. Relationship between hepatitis C virus infection and type 2 diabetes mellitus: meta-analysis. World Journal of Gastroenterology 2012; 18(14): 1642-1651. (IF: 2.901; HI: 69; Tier Q2); (ISI IF: 2.471)
  • Chew WK, Mak JW, Ambu S, Ignacuio Segarra. Toxoplasma gondii: determination of the onset of chronic infection in mice and the in vitro reactivation of brain cysts. Experimental Parasitology 2012; 130: 22-25. (IF: 2.216; HI: 48; Tier Q2); (ISI IF: 2.122)
  • Chew WK, Ignacio Segarra, Ambu S, Mak JW. Significant reduction of brain cysts caused by Toxoplasma gondii after treatment with spiramycin coadministered with metronidazole in a mouse model of chronic toxoplasmosis. Antimicrobial Agents and Chemotherapy 2012; 56: 1762-1768. (IF: 5.27; HI: 166; Tier Q1); (ISI IF: 4.841)
  • Mak JW. Mentorship in the research setting. International eJournal of Science, Medicine and Education (IeJSME) 2012; 6(1): 11-14. (IF: NA)
  • Mak JW. Pathology of lymphatic filariasis. International eJournal of Science, Medicine and Education (IeJSME) 2012; 6(Suppl 1): S80-S86. (IF: NA)
  • Pan Yan, Mak JW, Ismail R, Ong CE. In vitro modulatory effects of flavonoids on human cytochrome P450 2C8 (CYP2C8). Naunyn-Schmiedeberg’s Archives of Pharmacology 2012; 385 (5): 495-502. (SCI IF: 1.664; HI: 65; Tier Q1); (ISI IF: 2.647).
  • Pan Yan, Mak JW, Ong CE. Development and validation of HPLC methods for the determination of CYP2D6 and CYP3A4 activities. Current Pharmaceutical Analysis 2012; 8 (3): 219-224. (IF: 1.263; HI: 12; Tier Q2); (ISI IF: 1.155).
  • Pan Y, Tiong KH, Abd-Rashid BA, Ismail Z, Mak JW, Ong CE. Inhibitory effects of cytochrome P450 enzymes CYP2C8, CYP2C9, CYP2C19 and CYP3A4 by Labisia pumila extracts. J Ethnopharmacology 2012; 143 (2): 586-591. (SCI IF: 3.402; HI: 94; Tier Q1); (ISI IF: 3.104).

 

2013

 

  • Abdulsalam AM, Init Ithoi, Al-Mekhlafi HM, Khan AH, Ahmed A, Surin J, Mak JW. Prevalence, predictors and clinical significance of Blastocystis sp. in Sebha, Libya. Parasites and Vectors 2013; 6: 86; doi: 10.1186/1756-3305-6-86. (ISI IF: 2.94; SJR SCIMAGO IF: 3.034; HI: 15; Tier: Q1)
  • Chen DCK, Mak JW, Ooi SS, Mak KF, Chong KH. Effect of traditional Chinese medicine complex (TCM-D™) on experimentally induced diabetic mice. International e-Journal of Science, Medicine and Education (IeJSME) 2013; 7(1): 4-9.
  • Cho Naing, Mak JW, Kyan Aung, Wong Jadon VR. Efficacy and safety of dihydroartemisinin-piperaquine for the treatment of uncomplicated Plasmodium falciparum malaria in endemic countries: meta-analysis of randomised controlled studies. Transactions of the Royal Society of Tropical Medicine and Hygiene 2013; 107: 65-73. (ISI IF: 2.16; SJR SCIMAGO IF: 2.292; HI: 65; Tier: Q2)
  • Cho Naing, Mak JW. Mala Maung, Wong SF, AniIzzuani Mohd Kassim. Meta-analysis: The association between HIV infection and extrapulmonary tuberculosis. Lung 2013; 191(1): 27-34; doi 10.1007/s00408-012-9440-6. (ISI IF: 2.062; SJR SCIMAGO IF: 2.128; HI: 31; Tier: Q3)
  • Cho Naing, Mak JW, Nyunt Wai, Mala Maung. Diabetes and infection-Hepatitis C: Is there type 2 Diabetes excess in Hepatitis C infection? Current Diabetes Reports 2013; 13(3): 428-434; doi: 10.1007/s11892-013-0370-3. (ISI IF: 2.5; SJR SCIMAGO IF: 2.974; H: 35; Tier: Q1)
  • Cho Naing, Racloz V, Whittaker MA, Aung K, Mak JW, Tanner M. Efficacy and safety of dihydroartemisinin-peperaquine for treatment of Plasmodium vivax malaria in endemic countries: meta-analysis of randomized controlled studies. PLOS One 2013, 8(12): e78819. (ISI IF: 3.73; SJR SCIMAGO IF: 3.675; HI: 101; Tier: Q1).
  • Cho Naing, Whittaker MA, Nyut-Wai V, Reid SA, Wong SF, Mak JW, Tanner, M. Malaria and soil-transmitted intestinal helminths co-infection and its effect on anemia: a meta-analysis. Transactions of the Royal Society of Tropical Medicine and Hygiene 2013; 107: 672-683. (ISI IF: 2.16; SJR SCIMAGO IF: 2.292; HI: 65; Tier: Q2)
  • Ithoi I, Makmud R, Abdul Basher MH, Abdulsalam AM, Ibrahim J, Mak JW. Acanthamoeba genotype T4 detected in naturally-infected feline corneas found to be in homology with those causing human keratitis. Tropical Biomedicine 2013; 30(1): 131-140. (ISI IF: 0.921; SJR SCIMAGO: 0.921; HI: 12; Tier: Q2)
  • Ong CE, Yan Pan, Mak JW, Rusli Ismail. In vitro approaches to investigate cytochrome P450 activities: update on current status and their applicability. Expert Opinion on Drug Metabolism and Toxicology 2013; doi: 10.1517/17425255.2013.800482. [ISI IF: 3.119; SJR SCIMAGO IF: 3.298; HI: 33; Tier: Q1]
  • Pan Yan, Mak JW, Ong CE. Heterologous expression of human cytochrome P450 (CYP) 2C19 in Escherichia coli and establishment of RP-HPLC method to serve as activity marker. Biomedical Chromatography 2013; 27(7): 859-865; doi: 10.1002/bmc.2872. [ISI IF: 1.966; SJR SCIMAGO IF: 1.96; HI: 37; Tier: Q2]

 

2014

 

  • Ambu S, Yong SFY, Lim YAL, Mak JW, Chen DKF, Ooi SS, Lee SP, Tan TM, Goh MY. The chemical, heavy metal and microbial quality of well water in an urbanized village in Klang Valley. International e-Journal of Science, Medicine and Education (IeJSME), 2014; 8(3): 28-44. (MyCite IF: 0.024).
  • Chen JXJ, Lim PKC, Wong SF, Mak JW. Determination of the presence and levels of heavy metals and other elements in raw and commercial edible bird nests. Malaysian Journal of Nutrition 2014; 20(3): 377-391. (SCI IF: 0.662; H-Index: 9; Tier Q3)
  • Cho Naing, Whittakler MA, Nyunt Wai V, Mak JW. Is Plasmodium vivax malaria a severe malaria?: A ystematic review and meta-analysis. PLOS Negelected Tropical Diseases 2014; 8(8): e3071, doi: 10.1371/journal pntd.0003071. (ISI IF: 4.489; SCI IF: 4.564; H-Index: 49; Tier Q1)
  • Fong JH, Voon K, Ambu S. Mak JW. Phylogenetic analysis and identification of Sarcocystic spp. found in rodents in Peninsular Malaysia. International e-Journal of Science, Medicine and Education (IeJSME), 2014; 8(1): 12-17. (MyCite IF: 0.024).
  • Kew PE, Wong SF, Lim PKC, Mak JW. Structural analysis of raw and commercial farm edible bird nests. Tropical Biomedicine, 2014; 31(1): 63-76. (ISI IF: 0.921; SCI IF: 1.21; H-index: 14; Tier: Q2)
  • Kok YY, Chu WL, Phang SM, Shar Mariam M, Rakesh N, Lai PJ, Mak JW, Lim PKC, Pauline B, Khoo ASB. Inhibitory activities of microalgal extracts against Epstein-Barr virus (EBV) antgen expression in lymphoblastoid cells. Archives of Biological Sciences, Belgrade, 2014; 66(3): 1009-1024. (ISI IF: ; SCI IF: 0.607;
  • Mak JW. Conducting research that is both ethical and responsive to the health needs of a developing country. International e-Journal of Science, Medicine and Education (IeJSME), 2014; 8(1): 19-23. (MyCite IF: 0.024).
  • Ong CE, Pan Y, Abd-Rashid BA, Ismail Z, Ismail R, Mak JW. Studies on in vitro modulatory effect of Labisia pumila on CYP1A2, CYP2A6 and CYP3A4. Drug Metabolism Reviews, 2014; 45(Suppl 1): 82. (ISI IF: 5.622; SCI IF: 6.346; H-index: 69; Tier: Q1).
  • Pan Yan, Tiong KH, Badrul Amini Abd-Rashid, Zakiah Ismail, Rusli Ismail, Mak JW, Ong CE. In vitro effect of important herbal active constituents on human cytochrome P450 1A2 (CYOP1A2) activity. Phytomedicine, 2014; 21(12): 1645-1650. (ISI IF: 2.877; SCI IF: H-Index: ; Tier: Q2)
  • Pan Y, Tiong KH, Abd-Rashid BA, Ismail Z, Ismail R, Mak JW, Ong CE. Effect of eurycomanone on cytochrome P450 isoforms CYP1A2, CYP2A6, CYP2C8, CYP2C9, CYP2C19, CYP2E1 and CYP3A4 in vitro. Journal of Natural Medicines, 2014; 68(2): 402-6. DOI: 10.1007/s11418-013-0794-8. (SCI IF: 1.697; H-index: 20; Tier: Q1).
  • Rakesh Naidu, Lim VN, Mak JW, Moissinac K, Rahman A Jamal, Isa Mohd Rose, Yunus Gul Alif Gul, Lim PKC, Tan GJS. Protein expression of STAT3, pSTAT3, MMP-& and VEGF in colorectal adenocarcinoma: an immunohistochemical study. Journal of Cancer Therapy, 2014; 5: 1175-1185.
  • Tee CL, Ambu S, Mohandas K, Mak JW, Lokman Hakim Sulaiman, Murgaiyah M. Bacterial constituents of indoor air in a high throughput building in the tropics. Tropical Biomedicine, 2014; 31(3): 540-556. [BMS 1-01/2009(2)]. (ISI IF: 0.59; SCI IF: 1.058; H-index: 16; Tier: Q3).
  • Yap RMD, Lim PKC, Chan LL, Wong SF, Mak JW. Characterization of cyst and trophozoite proteins of environmental isolates of Acanthamoeba castellani by two-dimensional gel electrophoresis. Southeast Asian Journal of Tropical Medicine and Public Health, 2014; 45: 249-258. [IMU Internal Grant BMS 1-02/2011 (08)]. (ISI IF: 0.61; SCI IF: 0.729, H-index: 30, Tier: Q2).

 

2015

 

  • Chen Jennifer Xiao Jing, Wong SF, Lim PKC, Mak JW. Culture and molecular identification of fungal contaminants in edible bird nests. Food Additives & Contaminants: Part A 2015; DOI: 10.1080/19440049.2015.1101494. (ISI IF: 1.802; )
  • Cho Naing, Yong Poovorawan, JW Mak, Kyan Aung, Pirom Kamolratankul. Cost-utility analysis of an adjunctive recombinant activated factor VIIa for on-demand treatment of bleeding episodes in dengue haemorrhagic fever. Blood Coagulation and Fibrinolysis 2015; 26: 403-407; DOI: 10.1097/MBC.0000000000000280 (ISI IF: 1.38; SCI: 1.437; H-index: 59; Tier: Q2).
  • Cho Naing, Nyunt Wai V, Durham J, Whittaker MA, Win NN, Kyan Aung, Mak JW. A systematic review and meta-analysis of medical students’ perspectives on the engagement in research. Medicine 2015; 28: 1-9; DOI: 10.1097/MD.0000000000001089. (ISI IF: 5.723; SCI IF: 7.062; H-index: 111; Tier Q1).
  • Cho Naing, Whittaker MA, Mak JW, Kyan Aung. A systematic review of the efficacy of a single dose artemisinin-naphthoquine in treating uncomplicated malaria. Malaria Journal 2015; 14: 392; DOI 10.1186/s12936-015-0919-5. (ISI IF: 3.11; SCI IF: 2.019; H-index: 32; Tier: Q1).
  • Chong KT, Wong SF, Mak JW, Loh LC, Ho TM. Sero-prevalence study of IgE responses to allergens from Malaysian house dust (HDM) and storage mites (SM). Tropical Biomedicine, 2015; 32 (3): 524-530. (ISI IF: 0.850; SCI IF: 0.931; H-index: 20; Tier: Q3). [BMedSc BMS I-01/2011(02) and eSceince Fund (02-02-09-SF007)]
  • Pei Ern Kew, Suk Jiun Ling, Wong SF, Lim PKC, Mak JW. Isolation and identification of mites associated with raw and commercial farm edible bird nests. Tropical Biomedicine, 2015; 32(4): 761-775. (ISI IF: 0.850; SCI IF: 0.931; H-index: 20; Tier: Q3). [BMedSc BMS I-01/2012(03)]
  • Lim PKC, Yamasaki H, Mak JW, Wong SF, Chong CW, Yap IKS, Ambu S, Kumarasamy V. Field evaluation of a rapid diagnostic test to detect antibodies in human toxocariasis. Acta Tropica 2015; 148: 32-37; http://dx.doi.org/10.1016/j.actatropica.2015.04.011. (ISI IF: 2.519; SCI IF: 2.564; H-index: 69: Tier: Q1)
  • Teo KS, Cheah CW, Mak JW. Association between house dust mite (HDM) sensitisation, and asthma control using skin prick test and HDM antigen specific IgE levels in saliva of Malaysian children. International eJournal of Science, Medicine and Education 2015; 9(2): 3-12. (MyCite IF: 0.038; Tier Q4)

 

Last updated on 28 September  2016

 

 

 

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MS ISO/IEC 17025
TESTING
SAMM NO.650