MAI CHUN WAI

Designation/Title : Dr
Department: Pharmaceutical Chemistry
Tel: +603-2731 7596
Fax: +603- 8656 7229
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Education and Training

YPASM Research Fellow British Antarctic Survey, Cambridge, United Kingdom 2015-2016
PhD International Medical University, Malaysia 2014
Basic Teaching Licence International Medical University, Malaysia 2014
Research Fellow/ Visiting Researcher University of Strathclyde, Glasgow, United Kingdom 2013
Good Clinical Practice Certificate Ministry of Health, Malaysia 2012
RPh
Malaysia Pharmacy Board, Malaysia 2009
BPharm (Hons) First Class
International Medical University, Malaysia 2009

 

Research interests:

  • Drug Discovery
  • Cancer
  • Inflammation and Immunology
  • Pharmaceutical Care

 

Industrial Experience / Academic Experience:

  • Sultan Mizan Antartic Research Foundation (YPASM) Research Fellow, British Antarctic Survey, Cambridge, United Kingdom. 2015-2016
  • Research Fellow / Visiting Researcher, Strathclyde Institute of Pharmacy and Biomedical Sciences (SIPBS), University of Strathclyde, Glasgow, Scotland, United Kingdom 2013
  • Lecturer, School of Pharmacy, International Medical University, Malaysia 2010-present
  • Fully Registered Pharmacist, International Medical University, Malaysia 2010–present
  • Provisional Registered Pharmacist, Queen Elizabeth Hospital, Kota Kinabalu, Malaysia 2009-2010

 

Research projects/grants:

  • Fundamental Research Grant Scheme (FRGS) (2015-2018) for “System biology comparison between mice with single and co-infection from Toxoplasma gondii and/or Trypanosoma evansi” (Co-investigator - RM162 000.00)
  • Yayasan Penyelidikan Antartika Sultan Mizan (YPASM) Research Fellowship (2015-2016) for “The antifungal effects of bacteria isolated from Antarctic soil.” (Principle Investigator - RM 49,949.10)
  • International Medical University (IMU) (2015) for “Anticancer metabolite from Antartic orithogenic soil bacteria” (Principle Investigator – RM 12,000.00)
  • International Medical University (IMU) (2015) for “Evaluation of the anti-cancer properties of the 1, 3-dichlorobutan-2amine derivatives in vitro” (Co-investigator – RM 12,000.00)
  • International Medical University (IMU) (2015) for “Discovery of new anticancer pharmacophores through collaborative high-throughput phenotypic screen.” (Co-investigator – RM 15,000.00)
  • International Medical University (IMU) (2014-2016) for “Interprofessional learning amongst health professions students: a trajectory to consolidate professionalism” (Co-investigator - RM15,700.00)
  • International Medical University (IMU) (2014-2015) for “Molecular mechanisms and antitumor potentials of cudraflavone C in breast and colorectal cancers.” (Principle Investigator – RM 20,000.00)
  • International Medical University (IMU) (2014-2015) for “Effects of lutein (LUT) and zeaxanthin (ZEA) in modulating the DICER1 expression in human retinal pigment epithelium cells under oxidative stress.” (Co-investigator – RM 20,000.00)
  • Notthingham University Pump Priming Grant (2014-2015) for “Targeting Epigenetics for Cancer Therapy Invasive Lobular Carcinoma of Breast” (Co-investigator - RM20,000.00)
  • Malaysian Toray Science Foundation (MTSF) – Science and Technology Research Grant (2011-2012) for “Synthesis, Biological evaluation and structure activity relationship studies on shogaol analogues as new class of compounds targeting peroxisome proliferator activated receptor gamma (PPARg)” (Principle Investigator – RM 20,000.00)
  • International Medical University (IMU) (2010-2014) for “Discovery, Structure Activity Relationship Studies of Novel Small Molecules Targeting Toll-like Receptor-4 (TLR-4) and Their Molecular Mechanisms in Cancer.” (PhD student – RM 60,000.00)
  • Queen Elizabeth Hospital (Malaysia) Pharmacy Department Research Fund (2009-2010) for “Retrospective Study of Factors in Influencing the Outcome Among HIV-Infected Patients Started on HAART (RE-FIGHT) in Queen Elizabeth Hospital, Sabah.” (Principle Investigator)

 

Supervision of Postgraduates (MSc/PhD)
(Last 5 years – 2010-2015)

  • Ms Tham Shiau Ying (PhD Candidate). Notthingham University (Malaysia). (2015-present) Co-supervisor.

 

Professional affiliations:

International

  • Royal Society of Chemistry, United Kingdom : Member
  • Asia Young Pharmacist Group (AYPG) : Member
  • European Association for Cancer Research : Member / Ambassador
  • Taiwan Tzu Chi International Medical Association (TIMA) : Member

 

National

  • Malaysian Pharmaceutical Society-Young Pharmacist Chapter (MPS-YPC) : Deputy Chairperson
  • Malaysian Pharmaceutical Society : Life Member
  • Young Scientists Network-Academy of Sciences Malaysia : Member

 

Academic Awards:

  • 2015 Sultan Mizan Antarctic Research Foundation (YPASM) Research Fellow, British Antarctic Survey, Cambridge, United Kingdom.
  • 2015 Travel scholarship for “Workshop: Researcher Mobility in Drug Discovery” by Royal Society, AstraZeneca and Drug Metabolism Discussion Group at Milton Keynes, United Kingdom (7-8 December 2015)
  • 2015 Our CSR team won the PhAMA President’s Community Impact & Awareness Award 2015, a deworming project with Kampung Ulu Tual, Pos Sinderut, Pahang; a collaboration between Malaysian Pharmaceutical Society-Young Pharmacists Chapter, Center for Orang Asli Concerns (COAC), and IMU Strathclyde MPharm program Alumni (USAM).
  • 2015 Our research team won The Best Poster of Pharmacology at the Malaysian Pharmaceutical Society Pharmacy Scientific Conference (MPS-PSC) 2015. Kuala Lumpur, Malaysia.
  • 2015 Best Oral Presentation for Free Paper (Personal and Professional Development) by International Medical Education Conference (IMEC) 2015, Kuala Lumpur, Malaysia.
  • 2014 Our research team won the Y.S.P. SAH Best Research Paper Award by Tien Te Lee Biomedical Foundation (Taiwan) for the research paper : 6-Shogaol inhibits breast and colon cancer cell proliferation through activation of peroxisomal proliferator activated receptorγ(PPARγ) .Cancer Lett. 2013; 336 (1) : 127–139.
  • 2012 IMU Young Alumnus Award by International Medical University (IMU) to recognise IMU alumni who have made noteworthy contributions to community and society with significant personal and professional achievement.
  • 2012 Best Oral Presenter at the 1st International Nutraceutical and Cosmetic Sciences (ICNaCS). 22-23 October 2012, Kuala Lumpur, Malaysia.
  • 2012 Registration Fees Waiver Scholarship for the 1st International Nutraceutical and Cosmetic Sciences (ICNaCS). 22-23 October 2012, Kuala Lumpur, Malaysia.
  • 2012 Our research team won The Best Poster of Pharmaceutical Chemistry/ Pharmacology/ Traditional and Complementary Medicine at the Malaysian Pharmaceutical Society Pharmacy Scientific Conference (MPS-PSC) 2012. Kuala Lumpur, Malaysia.
  • 2011 Best Poster of Pharmaceutical Chemistry in the Malaysian Pharmaceutical Society Pharmacy Scientific Conference (MPS-PSC) 2011. Kuala Lumpur, Malaysia.
  • 2009 Dean’s List for being high academic achievement in the graduating class for the degree of Bachelor of Pharmacy (Hons) in the International Medical University, Malaysia.
  • 2009 Sanofi-Aventis Award for being excellence in research in the graduating class for the degree of Bachelor of Pharmacy (Hons) in the International Medical University, Malaysia.
  • 2009 Kotra Pharma Award for being excellence in pharmaceutical technology in the graduating class for the degree of Bachelor of Pharmacy (Hons) in the International Medical University, Malaysia.

 

Recent publications
(last 5 years – 2010 -2015)

  • Chun Wai Mai, Kok Seng Ivan Yap, Mee Teck Kho, Nor Hadiani Ismail, Khatijah Yusoff, Khozirah Shaari, Swee Yee Chin, Erin Swee Hua Lim. Mechanisms underlying the anti-inflammatory effects of Clinacanthus nutans Lindau extracts: inhibition of cytokine production and Toll-like receptor-4 activation. Frontiers in Pharmacology 2016; (in press) (IF: 3.8; Tier 1: Pharmacology)
  • Felicia Fei-Lei Chung, Chun Wai Mai, Pei Yuen Ng, Chee-Onn Leong. Roles of cytochrome P450 2W1 (CYP2W1) in colorectal cancers. Current Cancer Drug Targets 2016;16(1):71-8 (IF: 3.52; Tier 1: Pharmacology; Drug Discovery)
  • John Jeh Lung Tiong, Chun Wai Mai, Pou Wee Gan, Vivienne Sook Li Mak, James Johnson. Separation of prescribing and dispensing in Malaysia: The history, necessities and challenges. International Journal of Pharmacy Practice 2016 (in press) (IF: N/A; Tier 1: Pharmacy)
  • John Jeh Lung Tiong, Chun Wai Mai, Audrey Yong. Academic integrity of healthcare educators – Requisite for nurturing professionalism. Medical Education. 2015(49):1060-1062 (IF: 3.20; Tier 1: Education; Medicine)
  • Chun Wai Mai, Ramadas Anitha, John Jeh Lung Tiong, Pei Kuan Lai, Mallikarjuna Rao Pichika, Alexander Irvine Gray. Chemistry Content in the Pharmacy Curriculum: Relevance to Develop Pharmacists Fit-to-work in Diverse Pharmacy Profession Sectors. Indian Journal of Pharmaceutical Education and Research. 2015; 49(4):240-247 (IF: 0.219 ; Tier 2 : Pharmacology, Toxicology and Pharmaceutics (miscellaneous))
  • Chun Wai Mai, Marzieh Yaeghoobi, Noorsaadah Abd-Rahman, Yew Beng Kang, Mallikarjuna Rao Pichika. Chalcones with electron-withdrawing and electron-donating substituents: Anticancer activity against TRAIL resistant cancer cells, structure-activity relationship analysis and regulation of apoptotic proteins. European Journal of Medicinal Chemistry 2014: 77:378-87 (IF: 3.447 ; Tier 1 : Drug Discovery)
  • Polly Soo Xi Yap, Yik Tse Esther Chong, Yin Yau Wong, Xin Yee Lim, Jia Hui Ang, Heather Su Ling Goh, Mei Xuan Stephanie Lai, Chun Wai Mai, Ayuba Sunday Buru, Mallikarjuna Rao Pichika, Swee Hua Erin Lim. Antibacterial and antifungal testing of the different extracts of Dillenia obovata (Blume) Hoogl. World Journal of Pharmacy and Pharmaceutical Sciences. 2013; 2 (5): 3946-62 (IF: N/A; Tier: N/A)
  • Chun Wai Mai, Yew Beng Kang, Mallikarjuna Rao Pichika. Should a Toll-like receptor 4 (TLR-4) agonist or antagonist be designed to treat cancer? TLR-4: It’s expression and effects in ten most common cancers. Oncotargets and Therapy; 2013;6:1573-87 (IF: 2.311 ; Tier 1: Pharmacology)
  • Syed Shahzad Hasan, Pei Se Wong, Syed Imran Ahmed, David Weng Kwai Chong, Chun Wai Mai, Peter Pook, Therese Kairuz. Perceived Impact of Clinical Placements on Students Preparedness to Provide Patient-Centered Care in Malaysia. Currents in Pharmacy Teaching and Learning July 2013; 5(4): 303-10 (IF: N/A; Tier 2: Pharmacy)
  • Boon Shing Tan, Owen Kang, Chun Wai Mai, Kai Hung Tiong, Alan Soo-Beng Khoo, Mallikarjuna Rao Pichika, Tracey D. Bradshaw and Chee-Onn Leong. 6-Shogaol inhibits breast and colon cancer cell proliferation through activation of peroxisomal proliferator activated receptor  (PPAR). Cancer Letters Aug 9 2013;336(1):127-139. (IF: 5.621 ; Tier 1 : Cancer Research)

 

 

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