RATHBONE, MICHAEL JOHN

Designation/Title : Professor, Pharmaceutical Technology Department  Pharmacy
Tel: +603 2731 7414 
Fax: +603 8656 7239
E-mail : This e-mail address is being protected from spambots. You need JavaScript enabled to view it

 

 

 

Education and Training

PhD University of University of Aston, Birmingham, UK, 1986
BSc
Leicester Polytechnic, UK, 1980

 

Research interests:

  • Systemic drug delivery via mucosal sites
  • The development of modified release drug delivery systems
  • Controlled release veterinary drug delivery for farmed animals

 

Supervision of Postgraduates (MSc/PhD)
(Last 5 years – 2008-2012)

  • Mr Vladislav Syzov. University of Waikato, New Zealand. MEng. “Delivery of a coated bioactive from a rumen controlled-release device”.  2008.
  • Mr Bradley McLellan. University of Waikato, New Zealand. PhD.  “Characterisation of an in situ forming gel delivery system”. 2008.
  • Mr Sudeep Raj Bista. Griffith University, Australia. MMedRes. “Characterisation of the vagina of farmed animals”.  2010.

Professional affiliations:

  • Royal Pharmaceutical Society of Great Britain
  • Controlled Release Society

 

Academic Awards:

  • The Distinguished Service Award, Controlled Release Society
  • Fellow, Controlled Release Society

Recent publications
(last 5 years – 2008 -2012)

Journal

  • Martinez M, Michael M, Burgess D, Huynh M (2008) In Vitro and In Vivo Considerations Associated with Parenteral Sustained Release Products: A Review Based Upon Information Presented and Points Expressed at the 2007 Controlled Release Society Annual Meeting. Journal of Controlled Release, 129:  79-87.
  • Pathner SI, Rathbone, MJ, Senel S (2008) Current status and the future of buccal drug delivery systems. Expert Opinion on Drug Delivery. 5: 531-542.
  • Rathbone MJ, Martinez MN, Huynh M, Burgess D (2009) CRS/AAPS Joint Workshop on Critical Variables in the In Vitro and In Vivo Performance of Parenteral Sustained-Release Products. Dissolution Technologies. May Issue: 55-56.
  • Rathbone M, Brayden D (2009). Controlled release drug delivery in farmed animals: Commercial challenges and academic opportunities. Current Drug Delivery. 6: 383-390.
  • Martinez MN, Rathbone MJ, Burgess D., Huynh M (2010). Breakout session summary from AAPS/CRS joint workshop on critical variables in the in vitro and in vivo performance of Parenteral sustained release products. Journal of Controlled Release. 142: 2-7.
  • Rathbone MJ, Devarajan PV (2010) Animal Pharm. Pharmaceutical Manufacturing and Packaging Sourcer. August Issue: 37-44.
  • Bhattari S, Bunt C, Rathbone M, Alany RG (2011). Phase behaviour, rheological and mechanical properties of hydrophilic polymer dispersions. Pharmaceutical Development and Technology.  16(3): 259-268 (doi:10.3109/10837451003664073).
  • Khor KH, Campbell F, Rathbone MJ, Greer R, Mills PC (2011).  Acceptability and compliance of atenolol tablet, compounded paste and compounded suspension prescribed to healthy cats.  Journal of Feline Medicine and Surgery.  14 (2 ): 99-106. doi: 10.1177/1098612X11431521.
  • Khor KH, Campbell FE, Charles B, Norris R, Greer RM, Rathbone MJ, Mills PC.(2011). Comparative pharmacokinetics and pharmacodynamics of tablet, suspension and paste formulations of atenolol in cats. Journal of Veterinary Pharmacology and Therapeutics. Article first published online: 11 OCT 2011. DOI: 10.1111/j.1365-2885.2011.01342.x.
  • Gardyne SJ, Mucalo MR, Rathbone MJ (2011) The application of co-melt-extruded poly(e-caprolactone) as a controlled release drug delivery device when combined with novel bioactive drug candidates: Membrane permeation and Hanson dissolution studies Results in Pharma Sciences 1: 80–87.
  • Senel S, Rathbone MJ, Cansız M, Pather I (2012) Recent developments in buccal and sublingual delivery systems. Expert Opinion Drug Delivery.  9(6): 1-14.
  • Rathbone, MJ (2012) Delivering drugs to farmed animals using controlled release science and technology. IeJSME  6(1): S118-S128.


Books

  • Rathbone MJ, Hadgraft J, Roberts MS, Lane M (Editors). Modified-Release Drug Delivery Technology Volume I Drug Delivery Technologies for the Oral Mucosal and Gastrointestinal Tract Routes. Informa Healthcare, Inc., NY, USA. (2008).
  • Rathbone MJ, Hadgraft J, Roberts MS, Lane M (Editors). Modified-Release Drug Delivery Technology Volume 2 Drug Delivery Technologies for the Parenteral, Dermal, Pulmonary, Nasal, Vaginal and Ocular Routes. Informa Healthcare, Inc., NY, USA. (2008).
  • Rathbone MJ, Martinez MM (Theme Editors) Parenteral Issues and Hot Topics. Special Theme Issue. APPSPharmSciJ. (2010).
  • Siepmann J, Siegel RA, Rathbone MJ. (Editors). Fundamentals and Applications of Controlled Release Drug Delivery. 1st Edition, XIII, 592 p. Hardcover, ISBN 978-1-4614-0880-2. Springer, NY, USA. (2012).
  • Rathbone MJ, McDowell A (Editors).  Long Acting Animal Health Drug Products:  Fundamentals and Applications. 1st Edition, Springer, NY, USA.  In production. (2012).


Book Chapters

  • Pathner I, Senel S Rathbone MJ (2008) Oral mucosal drug delivery technologies in Rathbone MJ, Hadgraft J, Roberts MS, Lane M (Editors) Modified-Release Drug Delivery Technology Volume I Drug Delivery Technologies for the Oral Mucosal and Gastrointestinal Tract Routes. Informa Healthcare, Inc., NY, USA.
  • Rathbone MJ, Foster TP (2009) Veterinary Pharmaceutical Dosage  Forms. In: Florence AT, Siepmann J (Editors).  Modern Pharmaceutics. Applications and Advances; Volume 2. Drugs and the Pharmaceutical Sciences Series, Informa Healthcare, USA . ISBN9781420065640.
  • Siegel RA, Rathbone MJ (2012) Overview of Controlled Release Mechanisms. Chapter 2, pages 19-46.  In: Siepmann J, Siegel RA, Rathbone MJ. (Editors). Fundamentals and Applications of Controlled Release Drug Delivery. 1st Edition, 2012, XIII, 592 p. Hardcover, ISBN 978-1-4614-0880-2. Springer, NY, USA.
  • Siegel RA, Rathbone MJ (2012) The Shaping of Controlled Release Drug Product Development by Emerging Trends in the Commercial, Regulatory, and Political Macroenvironment. Chapter 18, pages 571-578.  In: Siepmann J, Siegel RA, Rathbone MJ. (Editors). Fundamentals and Applications of Controlled Release Drug Delivery. 1st Edition, 2012, XIII, 592 p. Hardcover, ISBN 978-1-4614-0880-2. Springer, NY, USA.
  • Rathbone MJ, Butler JM (2012) In Vitro Testing of Controlled Release Dosage Forms During Development and Manufacture. Chapter 5, pages 91-108.  In: Wilson CG. Crowley, PJ. (Editors). Controlled Release in Oral Drug Delivery.  1st Edition, 2012, XIII, 412 p. Hardcover ISBN 978-1-4614-1003-4. Springer, NY, USA.
  • Sabinis S, Rathbone MJ. (2012) Animal health markets and opportunities: Farmed animal landscape. pp 1-14. In: Michael J Rathbone and Arlene McDowell Editors. (2012). Long Acting Animal Health Drug Products. Springer, NY, USA. 389 pages. ISBN 978-1-4614-4438-1.
  • Fletcher JG, Rathbone MJ, Alany RG. (2012) Physicochemical principles of controlled release veterinary pharmaceuticals. pp 69-96. In: Michael J Rathbone and Arlene McDowell Editors. (2012). Long Acting Animal Health Drug Products. Springer, NY, USA. 389 pages. ISBN 978-1-4614-4438-1.
  • Higgins-Gruber S, Rathbone MJ, Brumfield J. (2012) In vitro drug release testing of veterinary pharmaceuticals. pp 193-220. In: Michael J Rathbone and Arlene McDowell Editors. (2012). Long Acting Animal Health Drug Products. Springer, NY, USA. 389 pages. ISBN 978-1-4614-4438-1.
  • Vandamme TF, Rathbone MJ. (2012) Long acting rumen drug delivery systems. pp 221-246. In: Michael J Rathbone and Arlene McDowell Editors. 2012. Long Acting Animal Health Drug Products. Springer, NY, USA. 389 pages. ISBN 978-1-4614-4438-1.
  • Rathbone MJ, Burke CR. (2012) Controlled release intravaginal veterinary drug delivery. pp 247-270. In: Michael J Rathbone and Arlene McDowell Editors. 2012. Long Acting Animal Health Drug Products. Springer, NY, USA. 389 pages. ISBN 978-1-4614-4438-1.
  • Baird AW, Brayden DJ, Rathbone MJ. (2012) Human:veterinary technology cross over. pp 359-375. In: Michael J Rathbone and Arlene McDowell Editors. 2012. Long Acting Animal Health Drug Products. Springer, NY, USA. 389 pages. ISBN 978-1-4614-4438-1.

 

 

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MS ISO/IEC 17025
TESTING
SAMM NO.650