C. MAYUREN

Designation/Title: Dr, Lecturer
Department: Life Sciences, School of Pharmacy, International Medical University
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Education and Training

PhD Vinayaka Missions University 2010
M.Pharm Tamilnadu Dr.M.G.R.Medical University 2005
B.Pharm Tamilnadu Dr.M.G.R.Medical University 2003

 

Research interests:

  • Diabetes, oxidative stress and insulin signaling
  • Cardiovascular pharmacology, calcium handling proteins and cardiac hypertrophy
  • Bioactive molecules drug research
  • Pharmacokinetic studies
  • Drug interactions

 

Research projects/grants:

  • Effect of madecassoside in reducing oxidative stress and blood glucose and in protecting the β-cells in streptozotocin-nicotinamide induced diabetes in rats
    Fundamental Research Grant Scheme (FRGS), Ministry of Higher Education (MOHE), Malaysia – RM 135 000
    2015-2017 - Principal Researcher
  • Antibiotic effects of 5-benzyl-[1,3]thiazolo[5,4-c]pyridine-2-amine in Streptozotocin-Nicotinamide induce diabetic rats
    IMU Research Fund, Bachelor of Medical Science - RM 20 000
    2014-2015 - Co-Researcher
  • An investigation on the hepatoprotective potential of the aqueous fractions of Auricularia polytricha in CCl4 intoxicated rats
    IMU Research Fund, Bachelor of Pharmacy - RM 6000
    2014 - Co-Researcher
  • Evaluation of Antimicrobial and Anti-Inflammatory Activity of Yemeni Honey and in Combination with Madecassoside against Propionibacterium Acnes in Peripheral Blood Mononuclear Cells (PBMC)
    IMU Research Fund, MSc Molecular Medicine - RM 10 000
    2014-2015 - Co-Researcher
  • Effect of trans isoferullic acid on CaMKII mediated phosphorylation in rat atrial and ventricular tissues
    IMU Research Fund, Bachelor of Pharmacy - RM 6000
    2014 - Principal Researcher
  • Investigation on pharmacokinetic profile of luteolin nanosuspension
    IMU Research Fund, Bachelor of Medical Science – RM 20 000
    2013-2014 - Co-Researcher
  • Evaluation of madecossoside, glimepiride and their combination on streptozotocin-nicotinamide induced diabetes in rats
    IMU Research Fund, Bachelor of Medical Science – RM 20 000
    2013-2014 - Principal Researcher
  • To compare and contrast the effects of naturally occurring phenols gallic acid and trans-isoferulic acid on the contractile function of atrial and ventricular cardiac preparations
    IMU Research Fund, Bachelor of Pharmacy - RM 6000
    2013 - Principal Researcher
  • Studies on the applicability of indigenously available natural gums in the design of mucoadhesive drug delivery systems.
    IMU Internal Research Grant – RM 20 000
    2012-2014 - Co-Researcher
  • Development of herbal formulation for the treatment of diabetes
    Research Promotion Scheme (RPS), AICTE, India. INR 1 500 000
    2011-2013 - Co-Researcher
  • Evaluation of a multifunctional staphylokinase variant with thrombin inhibition and antiplatelet aggregation activities produced from salt inducible E. coli GJ1158.
    UGC Research Grant, India.
    2010-2012 - Co-Researcher

 

Supervision of Postgraduates (MSc/PhD)
(Last 5 years – 2010-2014)

  • Hana Al-Baghaoi Abdullah – Master of Science (IMU) (2014-Present) - Co-Supervisor
    Evaluation of Antimicrobial and Anti-Inflammatory Activity of Yemeni Honey and in Combination with Madecassoside against Propionibacterium Acnes in Peripheral Blood Mononuclear Cells (PBMC)
  • Sravani – Master of Pharmacy (JNTU) (2011-2012) - Co-Supervisor
    Design and development of fast dissolving tablets of Glibenclamide
  • Manogna Kumari – Ph.D (JNTU) (2010-2012) - Co-Supervisor
    Interaction studies of selected anti-diabetic agents with selected anti-hypertensive agents and lipid lowering agents
  • Anmol Kumar – Ph.D (ANU) (2010-2012) - Co-Supervisor
    Evaluation of a multifunctional staphylokinase variant with thrombin inhibition and antiplatelet aggregation activities produced from salt inducible E. coli GJ1158
  • Kotaiah Babu Vadalasetty – Master of Pharmacy (JNTU) (2010-2011) – Principal Supervisor
    Influence of fenofibrate on the pharmacodynamics and kinetics of glibenclamide in rats and rabbit models.
  • Praveen Kumar Thumma – Master of Pharmacy (JNTU) (2008-2009) – Principal Supervisor
    Effect of angiotensin converting enzyme inhibitors on the pharmacodynamics and pharmacokinetics of gliclazide in normal and diabetic rats and rabbits
  • Siva Rama Krishna Maduppati – Master of Pharmacy (JNTU) (2008-2009) – Principal Supervisor
    Effect of angiotensin receptor blockers on the pharmacodynamics and pharmacokinetics of gliclazide in normal and diabetic rats and rabbits
  • Harshadha – Master of Pharmacy (JNTU) (2006-2007) – Principal Supervisor
    Effect of calcium channel blockers on the pharmacodynamics and pharmacokinetics of gliclazide in normal and diabetic rats and rabbits
  • Sudheer – Master of Pharmacy (JNTU) (2006-2007) – Co-Supervisor
    Design and development of membrane moderated transdermal drug delivery systems for propranolol hydrochloride
  • Narasimha Rao – Master of Pharmacy (JNTU) (2006-2007) – Co-Supervisor
    Design and development of membrane moderated transdermal drug delivery systems for diltiazem hydrochloride

 


Professional affiliations:

  • Tamil Nadu Pharmacy Council – 8219 A1
  • Association of Pharmaceutical Teachers of India – AP/LM-217

 

Academic Awards:

  • ...

Recent publications
(last 5 years – 2010 -2015)

Journal

  • Murthy EGK Talasila, Hemalatha Bavirisetti, Jithendra Chimakurthy, Mayuren Candasamy. Effect of Costus igneus: The insulin plant, on prediabetes and diabetes in neonatal streptozotocin rats. Journal of Health Sciences. 2014;4(3):1-7.
  • Mayuren Candasamy, Talasila Eswara Gopala Krishna Murthy, Kumar Shiva Gubiyappa, Dinesh Kumar Chellappan, Gaurav Gupta. Alteration of glucose lowering effect of glibenclamide on single and multiple treatments with fenofibrate in experimental rats and rabbit models. Journal of Basic and Clinical Pharmacy. 2014;5(3):62-67.
  • Gaurav Gupta, Gopala Krishna, Dinesh Kumar Chellappan, Kumar Shiva Gubbiyappa, Mayuren Candasamy, Kamal Dua. Protective effect of pioglitazone, a PPARγ agonist against acetaminophen-induced hepatotoxicity in rats. Molecular and Cellular Biochemistry. 2014;393(1-2):223-228.
  • Gaurav Gupta, Mohammad Afzal, Sheba Rani David, Rohit Verma, Mayuren Candasamy, Firoz Anwar. Anticonvulsant activity of Morus alba and its effect on brain gamma-aminobutyric acid level in rats. Pharmacognosy Research. 2014;6(2):188-189.
  • T Murthy, MK Kommineni, C Mayuren. Influence of losartan on the hypoglycemic activity of glimepiride in normal and diabetic rats. Therapeutic Advances in Endocrinology and Metabolism.2013;4(5):133-138.
  • A Kumar, KK Pulicherla, C Mayuren, S Kotra, KR Sambasiva Rao. Evaluation of a multifunctional staphylokinase variant with thrombin inhibition and antiplatelet aggregation activities produced from salt inducible E. coli GJ1158. Canadian Journal of Physiology and Pharmacology. 2013;91(10): 839-847.
  • KK Manogna, GK Murthy, C Mayuren. Influence of lovastatin on the pharmacodynamics and pharmacokinetics of glimepiride in rats and rabbits. Inventi Impact: pharmacokinetics & pharmacodynamics.2013(2)
  • D Visagaperumal, C Mayuren, N Anbalagan. A facile synthesis of mutual prodrug of diclofenac sodium and paracetamol and its preformulation studies. Indian Drugs. 2012;49(10):25-29
  • V. Saikishore, G. Srikanth, Ch. Pooja, Y. Mrudula, R. Pavani, Ch. Jyosthna and C. Mayuren. Design and development of fast dissolving tablets of glibenclamide. Research Journal of Pharmaceutical Dosage Forms and Technology. 2011; 3(5):225-229.
  • Mayuren Candasamy, Nagabhushanam Kammili, Sunil MK Varikutti, Balakrishna Pamarthi, Rajesh Chennu and Mrudhula Alla. Hypoglycaemic and anti-hyperglycaemic effect of Jamboola, a polyherbal ayurvedic formulation in normal and alloxan induced diabetic rats. Eur. J. Exp. Biol. 2011; 1(2):109-114.
  • Rama K. Raparla, Eswara G.K.M. Talasila, Santhosh K. Mankala and Candasamy Mayuren. Mucoadhesive microcapsules of glipizide formulated with gum kondagogu: in vitro and in vivo evaluation. Lat. Am. J. Pharm. 2011; 30(7):1253-1259.
  • V.Sai Kishore, T.E.G.K.Murthy and C.Mayuren. Comparative in vivo evaluation of diltiazem hydrochloride after oral and transdermal administration in rabbits. Research J. Pharm. and Tech. 2011; 4(1): 150-154.
  • V.Sai Kishore, T.E.G.K.Murthy and C.Mayuren. Comparative in vivo evaluation of propranolol hydrochloride following oral and administration in rabbits. Asian J. Research Chem. 2011; 4(3): 461-465.
  • G.Saravanan, C.R.Prakash, T.Paneer Selvam, P.Dinesh Kumar and C.Mayuren. Synthesis and anti-inflammatory activity of 2,4-disubstituted thiazoles. Indian Journal of Heterocyclic Chemistry 2010; 20: 193-194.
  • Candasamy Mayuren, Vudumula Varun Reddy, Srikakulam Vishnu Priya, Vallampatla Anusha Devi. Protective effect of Livactine against CCl4 and paracetamol induced hepatotoxicity in adult wistar rats. North Am. J. Med. Sci. 2010; 2: 491-495.
  • K.Swapna Kumari, T.E.G.K.Murthy and C.Mayuren. Influence of physical form on in vitro and in vivo performance of olanzapine. Pharmanest 2010; 1 (1):51-57.

Books

  • Title: Pharma Inspectrum – A Complete Spectra for all Pharmacy Competitive Exams. 2012, Novo Media, Hyderabad 500017, India. (Co-Author)
 

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