LIM CHOOI LING

Designation/Title : Dr
Department: Human Biology
Tel: 03-27317611 (Ext. 2761)
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Education and Training

PhD
University Putra Malaysia 2010
BSc
University Putra Malaysia 2006

 

Research interests:

  • TGF-β signaling in liver fibrosis and quiescence of hepatic stellate cells
  • Secondary metabolites of Actinomyces (Streptomyces sp.)
  • Bioactivity of edible bird nest on UV-irradiated keratinocytes

Research projects/grants:

  • Comparative effects of edible bird nest, ‘sea bird nest’, and carrageenan on aquaporin-3 expression and migration of UV-irradiated normal human epidermal keratinocytes,
    Bachelor of Medical Science (BMedSc) project, International Medical University
    Mar 2012 – Nov 2012 – Principal Researcher
  • Epidermal growth factor receptor (EGFR)-mediated rescue of downregulated aquaporin 3 (AQP3) in ultra violet (UV)-irradiated human keratinocytes by edible birdnest (EBN),
    Fundamental Research Grant Scheme (FRGS), Ministry of Higher Education (MOHE),
    2011 – 2012 – Principal Researcher
  • Antioxidant and proliferative activity of edible birdnest (EBN) in human epidermal cells,
    Bachelor of Pharmacy Semester 7 Research Project, International Medical University,
    Jul 2011 – Dec 2011 – Principal Researcher
    Supervision of Postgraduates (MSc/PhD)



Supervision of Postgraduates (MSc/PhD)
(Last 5 years – 2008-2012)

  • Chua Ming Jang  - MSc. (2010 – Present)  - Co-supervisor
    Inhibition of cancer cell proliferation and survival through synergistic effects of traditional anti-cancer drug action in combination with target knockdown of cancer-related genes

Professional affiliations:

  • Member of the Malaysian Society for Biochemistry and Molecular Biology (MSBMB), 2010 – current

Academic Awards:

 

  • Nutrition Society of Malaysia (NSM) 21st Scientific Conference 30-31 March 2006 (Best Poster Prize – Consolation)
  • KUTPM Students Symposium Series on Biomedicine No: 2 (3rd Best Oral Presenter) 2006
  • Teguh Pharma Award 2006 for Excellence in Pathology [BSc (Biomedical Science) Hons]
  • National Science Fellowship Scholarship (Ph.D.) 2006-2009
  • International Seminar of Indonesian Society for Microbiology (ISISM), 4 – 7 Oct 2010 (Best Oral Presenter)

 

Recent publications
(last 5 years – 2008 -2012)

  • Guo J, Hong F, Loke J, Yea S, Lim CL, Lee U, Mann D, Walsh M, Sninsky JJ, Friedman SL. (2010) A DDX5 S480A polymorphism is associated with increased transcription of fibrogenic genes in hepatic stellate cells. J Biol Chem; 285(8):5428-37.
  • C.L. Lim, R.Y. Koh, H.F. Seow. Attenuation of liver myofibroblast activation by a small-molecule TGF-β receptor I inhibitor. In: Spandidos DA, editor. Proceedings of the Abstracts of the 16th World Congress on Advances in Oncology and 14th International Symposium on Molecular Medicine; 2011 Oct 6-8; Rhodes Island, Greece. Int J Mol Med 2011;28(S1):S25.
  • Chooi Ling, Lim, Rhun Yian, Koh, Sharmili Vidyadaran, Maha Abdullah, Coy Choke, Ho, Johnny C. Loke, Scott L. Friedman, Heng Fong, Seow. Streptomyces sp. H6552 Extract: Inhibitor of Hepatic Stellate Cell Activation. International Seminar of Indonesian Society for Microbiology (ISISM 2010) 2010 Oct 4-7; Bogor, Indonesia.
  • Chooi Ling, Lim, Rhun Yian, Koh, Sharmili Vidyadaran, Maha Abdullah, Coy Choke, Ho, Johnny C. Loke, Scott L. Friedman, Heng Fong, Seow. Bioactive fraction of Streptomyces sp. H6552 attenuates liver fibrosis in vitro. 35th Annual Conference of the Malaysian Society for Biochemistry & Molecular Biology, 2010 Jul 27-28; Selangor, Malaysia.







 

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