KOK YIH YIH

Designation/Title : Dr
Department: School of Medical Sciences, Human Biology
Tel: 03-2731 7572
Fax: 03-8656 7229
E-mail : This e-mail address is being protected from spambots. You need JavaScript enabled to view it

 

Education and Training

PhD
International Medical University
(Algal Biotechnology)
2010
MSc University of Putra Malaysia
(Animal Biotechnology)
2002
BSc
University of Putra Malaysia
(Hons) Biotechnology
1999

 

Research interests:

  • Environmental Pollutants
  • Environmental allergens

 

Research projects/grants:

National Research & Development Grants:

  • Assessment of the combined effects of nutrients enrichment and pesticide toxicity on various biomarkers in microalgae, from Ministry of Higher Education, Fundamental Research Grant Scheme (FRGS), 2014-2016 RM100,000 (as co-investigator, with Prof Chu Wan Loy, Dr Wong Chiew Yen, Dr Tan Boon Keat, Prof Phang Siew Moi (UM))
  • Allergenic potential of airborne microalgae isolated from Malaysia, from Ministry of Higher Education (FRGS), 2013-2015, RM149,500 (as Principal Investigator with Prof Chu Wan Loy, Prof Phang Siew Moi (UM), Dr Wong Shew Fung, AP Dr Srikumar Chakravarthi, AP Dr Chew Fook Tim (NUS) )
  • Induction of Programmed Cell Death (PCD) in Algae by Environmental Toxicants, from Department of Higher Education, Fundamental Research Grant Scheme (FRGS), 2010-2013 RM75,000 (as co-investigator, with Prof Chu Wan Loy, International Medical University, Prof Phang Siew Moi (UM))
  • Effects of airborne algae on contractility of tracheal smooth muscle, 2014, RM20,000 (as Principal Investigator with Assoc Prof Dr Chen Yu Sui, Prof Chu Wan Loy)
  • Effects of salinity on the toxicity of single-walled carbon nanotubes in marine microalgae, 2015, RM4,500 (as Principal Investigator with Prof Chu Wan Loy, Dr Tan Boon Keat).
  • Nanoparticle toxicity in marine microalgae: characterisation of particle size and zeta potential, 2014, RM3,000 (as Principal Investigator with Prof Chu Wan Loy, AP Dr Leong Chee Onn)
  • Assessment of the toxicity of functionalised single-walled carbon nanotubes in two marine microalgae, 2013, RM20,000 (as Principal Investigator with Prof Chu Wan Loy, AP Dr Leong Chee Onn)
  • Assessment of the toxicity of nanomaterials in marine microalgae, from International Medical University Bachelor of Science (Medical Biotechnology), 2013, RM3,000 (as Principal Investigator with Prof Chu Wan Loy, AP Dr Leong Chee Onn)
  • Effect of aqueous extract and phycocyanin from Spirulina platensis on expression of Epstein-Barr virus (EBV) latent and lytic genes in lymphoblastoid cell lines, from International Medical University Bachelor of Medical Science, 2012, RM20,000 (as Principal Investigator with Prof Chu Wan Loy)
  • Inhibition of Spirulina platensis aqueous extract and phycocyanin against the expression of Epstein - Barr virus lytic proteins, from International Medical University Bachelor of Science Medical Biotechnology, 2011, RM6,000 (as Principal Investigator with Prof Chu Wan Loy).
  • Inhibitory activity of algal compounds against Epstein-Barr virus lytic cycle and proteins expression, from International Medical University Bachelor of Medical Science, 2011, RM20,000 (as Principal Investigator with Prof Chu Wan Loy).
  • Influence of nitrogen and phosphorus levels on heavy metal toxicity in microalgae, from International Medical University, 2012, RM20,000 (as co-investigator, with Prof Chu Wan Loy, International Medical University)
  • Influence of nitrogen source on the sensitivity of microalgae to triclosan, from International Medical University, 2010, RM9,000 (as co-investigator, with Prof Chu Wan Loy, International Medical University)
  • Antioxidant and antiproliferative activities of the algal pigment fucoxanthin. International Medical University Bachelor of Science Medical Biotechnology, 2011, RM9,000 (as co-investigator, with Prof Chu Wan Loy, International Medical University)
  • Acid phosphatase bioassay for the assessment of heavy metal toxicity in algae. International Medical University Bachelor of Medical Science, 2011, RM20,000 (as co-investigator, with Prof Chu Wan Loy, International Medical University)
  • Influence of urea levels on the sensitivity of microalgae to triclosan. International Medical University Bachelor of Pharmacy, 2011, RM9,000 (as co-investigator, with Prof Chu Wan Loy, International Medical University)

 

Supervision of Postgraduates (MSc/PhD)
(Last 5 years – 2010-2014)

  • Dang Nguk Ling (MSc candidate). Project title: Effect of heavy metal toxicity on cell death and oxidative stress in Dunaliella tertiolecta and Pavlova gyrans. Co-supervisor. Researchers: Prof Chu Wan Loy, Prof Phang Siew Moi (UM). (2011-2014)
  • Chin Yin Yien (MSc candidate). Project title: Assessment of the toxicity of pharmaceuticals in microalgae based on cell viability and oxidative stress biomarkers. Co-supervisor. Researchers: Prof Chu Wan Loy, Prof Phang Siew Moi (UM). (2012-2014)
  • Hemavathy Subramaniam (PhD candidate). Project title: Immunomodulatory Effects of Tocotrienol and Spirulina on Tumourigenesis using A Mouse Model of Breast Cancer. Co-supervisor. Researchers: Prof Chu Wan Loy, Prof Dr Ammu Radhakrishnan, Dr Sri Kumar Chakravarthi (Perdana University), Dr Kanga Rani Selvaduray (MPOB). Start date: 2012
  • Choong Siew Ling (MSc candidate). Project title: Allergenic potential of airborne algae isolated from Malaysia. Co-supervisor. Researchers: Prof Chu Wan Loy, Dr Wong Shew Fung. Start date: 2014
  • Juay Harn Li (MSc candidate). Project title: Skin allergenicity of airborne and soil algae isolated from Malaysia. Resaerchers: Prof Chu Wan Loy, Dr Wong Shew Fung. Start date: 2014

Professional affiliations:

  • ...

Academic Awards:

  • ....

Recent publications
(last 5 years – 2010 -2014)

  • Kok YY, Chu WL, Phang SM, Mohamed SM, Naidu R, Lai PJ, Ling SN, Mak JW, Lim PKC, Balraj P, Khoo ASB. Inhibitory activity of microalgal extracts against the expression of Epstein-Barr virus (EBV) antigens in lymphoblastoid cells. Arch. Biol. Sci., Belgrade. 2014; 66(3): 1009-1024.
  • Yee MWL, Khiew PS, Tan YF, Kok YY, Cheong KW, Chiu WS, Leong CO. Potent antifouling silver-polymer nanocomposite microspheres using ion-exchange resin as templating matrix. Colloids and Surfaces A: Physicochem. Eng. Aspects. 2014; 457: 382–391
  • Kok YY, Lim YM, Kartini A, Aspollah S, Nashriyah M, Rahmani M and Ali AM. Anti-tumour promoting activity and antioxidant properties of girinimbine isolated from the stem bark of Murraya koenigii S. Molecules. 2012; 17(4): 4651-60.
  • Kok YY, Chu WL, Phang SM, Mohamed SM, Naidu R, Lai PJ, Ling SN, Mak JW, Lim PKC, Balraj P, Khoo ASB. Inhibitory activiites of microalgal extracts against Epstein-Barr virus DNA release from lymphoblastoid cells. Journal of Zhejiang University-Science B (Biomedicine and Biotechnology) 2011; 12(5): 335-345.
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