KANG YEW BENG

Designation/Title : Associate Professor
Department: Pharmaceutical Chemistry
Tel: 03-2731 7242
Fax: 03-86567229
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Education and Training

PhD Australian National University 1994
BSc (Hons)
University of Western Australia 1990

 

Research interests:

  • Surface Chemistry/Physical Chemistry
  • Organic Synthesis
  • Organometallic Synthesis
  • E-Learning
  • Big Data Analytics

 

Research Projects/Grants:

2010

  • Discovery, Structure-Activity Relationship Studies of Novel Small Molecules Targetting Toll-like Receptor-4 (TLR-4) and Their Mechanisms of Action in Cervical Cancer. Project in collaboration with Mallikarjurna Pichika Rao and Mai Chun Wai. (co-researcher)

2011

  • Development and Characterisation of Solid Lipid Nanoparticles as Nano-carrier to Deliver Drugs Across the Blood-brain Barrier. Project in collaboration with PS Rajinikanth and Lim Wei Meng. (co-researcher)

2012

  • Synthesis and in vitro Evaluation of Novel Compounds Containing Phenylpropanoid Pharmacophore Targetting Pyruvate Kinase in Methicillin Resistant Staphylococcus aureus. Project in collaboration with Mallikarjurna Pichika Rao et al. (co-researcher)
  • Production of Biocompatible and Biodegradable Waterborne Porous Polyurethane Scaffolds from Palm oil-Based Polyester Polyol and Cellulose nanocrystals for Tissue Engineering. Project in collaboration with Lee Choy Sin et al. (co-researcher)

 

Supervision of Postgraduates (MSc/PhD)
(Last 5 years – 2008-2012)

  • Khalid Ahmad Sheikh (PhD University of Strathclyde, 2012)
    Formulation and characterisation of Palm Oil-based Topical Emulsions.
  • Mr Mai Chun Wai (MSc/PhD IMU – Present) – Co-Supervisor
    Discovery, Structure-Activity Relationship Studies of Novel Small Molecules Targetting Toll-like Receptor-4 (TLR-4) and Their Mechanisms of Action in Cervical Cancer.
  • Mr Lim Wei Meng (MSc IMU – Present) – Co-Supervisor
    Development and Characterisation of Solid Lipid Nanoparticles as Nano-carrier to Deliver Drugs Across the Blood-brain Barrier.


Professional affiliations:

  • Member of the American Chemical Society since 2002
  • Member of the Royal Australian Chemical Society from 1990 - 1997

 

Academic Awards:

  • ....

Recent publications
(last 5 years – 2008 -2012)

Journal

  • Sheikh KA, Rouse JJ, Kang YB, Eccleston GM. Influence of hydration state and homologue composition of magnesium stearate on the properties of liquid paraffin lipogels using quality by design approach. (2010). J Pharm Pharmacol 62(10), 1338-9.
  • Sheikh KA, Kang YB, Rouse JJ, Eccleston GM. Influence of hydration state and homologue composition of magnesium stearate on the physical chemical properties of liquid paraffin lipogels. International Journal of Pharmaceutics 2011; 411; 121-127. [IF: 2.93].
  • Tan Eng Lai, Kang Yew Beng, Pichika R Mallikarjuna, Davamani A Fabian, Adinarayana Gorajana, Chooi Ling Lim. S 32 Bioactive Molecules: current trends in discovery, synthesis, delivery and testing. International e-Journal of Science, Medicine & Education, 4/2013; 7(Suppl 1): 32-46.
  • Mallikarjuna Rao Pichika, Beng Kang Yew, Seik Weng Ng. 2-Methoxy-4-(prop-2-en-1-yl)phenyl4-methoxybenzoate.
Acta Crystallographica Section E (2013) E69, o819.
  • Mallikarjuna Rao Pichika, Yew Beng Kang, Seik Weng Ng.
2-Methoxy-4-(prop-2-en-1-yl)phenylbenzoate.
Acta Crystallographica Section E (2013) E69, o1088.
  • 2-Methoxy-4-(prop-2-en-1-yl)phenyl2,4-dichlorobenzoate
Mallikarjuna Rao Pichika, Beng Kang Yew, Seik Weng Ng
Acta Crystallographica Section E (2013) E69, o1089.
  • Should a Toll-like receptor 4 (TLR-4) agonist or antagonist be designed to treat cancer? TLR-4: its expression and effects in the ten most common cancers. Chun Wai Mai, Yew Beng Kang, Mallikarjuna Rao Pichika; OncoTargets and Therapy 2013: 6 1-15.
  • Chalcones with electron-withdrawing and electron-donating substituents: Anticancer activity against TRAIL resistant cancer cells, structure-activity relationship analysis and regulation of apoptotic proteins. Mallikarjuna Pichika, Chun-Wai Mai; Yaeghoobi Marzieh; Noorsaadah Abd-Rahman; Yew-Beng Kang; European Journal of Medicinal Chemistry.

 

 

 

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