CHAN LI LI

Designation/Title : Dr, Lecturer
Department: Pathology Division, School of Medicine
Tel: 03-27317604
Fax: 03-86567299
E-mail : This e-mail address is being protected from spambots. You need JavaScript enabled to view it

 

Education and Training

PhD International Medical University 2010
MSc University of Malaya 2004
BSc University of Malaya 1999

 

Research interests:

  • Medical Parasitology
  • Medical Microbiology

Research projects/grants:

  • Functional roles of DNA-methyltransferase and histone-deacetylases on the regulation of genes encoding virulence-associated proteins in Acanthamoeba species. FRGS/1/2014/SKK05/IMU/03/1; RM 114,920.00 (2014-2016).
  • Effects of water residuals on Anti-Acanthamoeba properties of multipurpose contact lens solutions. BP I-01/11(24)2014; RM9,000 (2014)
  • Quantitative and Qualitative Analysis of the Antimicrobial Activity of Chinese Medicinal Herbs Used Alone or In Combination against Human Pathogenic Bacteria. BPharm B0110_Res162013; RM6,000 (2013)
  • Comparative Evaluation of Different Staining Methods for the Detection of Bacterial Endosymbionts within Acanthamoeba species. BMSc I/01/2011(02)2013; RM2,000 (2013)
  • Evaluation of Escherichia coli, Streptococcus pneumoniae and human glial cells as food source on modulating the pathogenic characteristics of Acanthamoeba towards BALB/c mice. BMS I01/2012 (06); RM20,000 (2012)
  • Antimicrobial Properties of Fifteen Traditional Chinese Medicines against Bacteria Which Can Cause Human Infections. BPharm B0109_Res012012; RM6,000 (2012)
  • Detection and identification of Acanthamoeba spp. and other microbial contamination in contact lens storage cases of students at the International Medical University. BMS I02-2011(07); RM20,000 (2011)
  • Different microorganism food sources modulate the pathogenic characteristic of environmental Acanthamoeba spp. FRGS/2/2010/SKK/IMU/03/2; RM56,000 (2012-2012)
  • Detection of Acanthamoeba castellani and Acanthamoeba polyphaga organisms in tissues of experimentally infected rats. BMS I02-2010(01); RM20,000 (2010)

 

Supervision of Undergraduates and Postgraduates

  • Wong Yi Hao (MSc; Co-supervisor). Functional roles of DNA-methyltransferase and histone-deacetylases on the regulation of genes encoding virulence-associated proteins in Acanthamoeba species. 2014-2016
  • Suresh Shanmugham (PhD; Co-supervisor). Controlled delivery of microbicides from intra-vaginal polymer matrices for the treatment and prevention of trichomoniasis and bacterial vaginosis. 2014-2016.
  • Hua Loon Leng, Lee Kai Sheng, Lim Eng Yew (BP; Main supervisor). Effects of water residuals on Anti-Acanthamoeba properties of multipurpose contact lens solutions. 2014.
  • Low Chia Ren, Fiona Chai Yuan Peng (BP; Main supervisor). Quantitative and Qualitative Analysis of the Antimicrobial Activity of Chinese Medicinal Herbs Used Alone or In Combination against Human Pathogenic Bacteria. 2013.
  • Hevanshi Vidhushika Fernando (BMed Sc; Co-supervisor). Controlled delivery of tinidazole from intra-vaginal polymer matrices for the treatment of trichomoniasis. 2013.
  • Chong Pei Yee (BMed Sc; Main supervisor). Evaluation of Escherichia coli, Streptococcus pneumoniae and human glial cells as food source on modulating the pathogenic characteristics of Acanthamoeba towards BALB/c mice. 2012.
  • Wong Ee Lynn, Teh Chai Yin (BP; Main supervisor). Antimicrobial Properties of Fifteen Traditional Chinese Medicines against Bacteria Which Can Cause Human Infections. 2012.
  • Eunice Ewe Mei Ning (BMed Sc; Main supervisor). Detection and identification of Acanthamoeba spp. and other microbial contamination in contact lens storage cases of students at the International Medical University. 2011.
  • Ray Yap Ming Dao (BMed Sc; Co-supervisor). Characterization of cyst and trophozoite proteins of Acanthamoeba castellani and Acanthamoeba polyphaga isolates by SDS-PAGE and two-dimensional (2-D) gel electrophoresis. 2011.
  • Tiong Kor Woi (BMed Sc; Main supervisor). Detection of Acanthamoeba castellani and Acanthamoeba polyphaga organisms in tissues of experimentally infected rats. 2010.

Professional affiliations:

  • Malaysian Society of Parasitology and Tropical Medicine

 

Academic Awards:

  • ...

Publications and presentations

  • Dao YR, Chooi LP, Li CL, Fung WS, Wah MJ. Characterization of cyst and trophozoite proteins of environmental isolates of Acanthamoeba castellanii by two-dimensional gel electrophoresis.
  • Southeast Asian J Trop Med Public Health. 2014 Mar;45(2):249-58
  • Chong PY, Chan LL, Mak JW, Stephen A. Molecular and Morphological Characterisation of Acanthamoeba Bacterial Endosymbionts Isolated from Dust Samples of Air-conditioners, in 49th Annual Scientific Conference Malaysian Society of Parasitology and Tropical Medicine
  • Ewe MNE, Chan LL, Mak JW. Detection and Molecular Identification of Acanthamoeba spp. and Other Microbial Contamination in the Contact lens Storage Cases and the role of Domestic Tap Water in the Contamination, in  the 37th Annual Conference of the Malaysian Society for Biochemistry and Molecular Biology, Sime Darby Convention Centre, Kuala Lumpur.
  • Tiong KW, Chan LL, Mak JW.Detection of Acanthamoeba organisms in tissue of experimentally infected rats using Haematoxylin and Eosin and Immunohistochemical staining, in in the 36th Annual Conference of the Malaysian Society for Biochemistry and Molecular Biology, Eastin Hotel, Petaling Jaya.
  • LL Chan, JW Mak, YT Low, TT Koh, I Ithoi, SM Mohamed. Isolation and Characteriszation of Acanthamoeba Spp. from Air-conditioners in Kuala Lumpur, Malaysia. Acta Trop. 2011 Jan; 117(1):23-30. doi: 10.1016/j.actatropica.2010.09.004.
  • S Ambu, WL Chu, JW Mak, SF Wong, LL Chan, ST Wong. Environmental health and building related illnesses. IeJSME 2008: 2 (Suppl 1): S11-S18
 

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